| Mass-like extramedullary hematopoiesis: imaging features. | |
| | |
MedLine Citation:
|
PMID: 22101909 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE: To report the imaging appearances of mass-like extramedullary hematopoiesis (EMH), to identify those features that are sufficiently characteristic to allow a confident diagnosis, and to recognize the clinical conditions associated with EMH and the relative incidence of mass-like disease. MATERIALS AND METHODS: We retrospectively identified 44 patients with EMH; 12 of which (27%) had focal mass-like lesions and formed the study group. The study group consisted of 6 male and 6 female subjects with a mean age of 58 years (range 13-80 years). All 12 patients underwent CT imaging and 3 of the 12 patients had undergone additional MR imaging. The imaging characteristics of the extramedullary hematopoiesis lesions in the study group were analyzed and recorded. The patient's clinical presentation, including any condition associated with extramedullary hematopoiesis, was also recorded. RESULTS: Ten of the 12 (83%) patients had one or more masses located along the axial skeleton. Of the 10 patients with axial masses, 9 (90%) had multiple masses and 7 (70%) demonstrated internal fat. Eight patients (80%) had paraspinal masses and 4 patients (40%) had presacral masses. Seven patients (70%) had splenomegaly. Eleven of the 12 patients had a clinical history available for review. A predisposing condition for extramedullary hematopoiesis was present in 10 patients and included various anemias (5 cases; 45%), myelofibrosis/myelodysplastic syndrome (4 cases; 36%), and marrow proliferative disorder (1 case; 9%). One patient had no known predisposing condition. CONCLUSION: Mass-like extramedullary hematopoiesis most commonly presents as multiple, fat-containing lesions localized to the axial skeleton. When these imaging features are identified, extramedullary hematopoiesis should be strongly considered, particularly when occurring in the setting of a predisposing medical condition. |
| | |
Authors:
|
Andrew W Ginzel; Mark J Kransdorf; Jeffrey J Peterson; Hillary W Garner; Mark D Murphey |
Related Documents
:
|
22242059 - Atypical presentation of focal nodular hyperplasia. 20121589 - A potential means of improving the evaluation of deformity corrections with taylor spat... 21841509 - Monitoring and prediction of intracranial hypertension in pediatric traumatic brain inj... 21927699 - Radiofrequency ablation of renal tumors: our experience. 21853039 - Predicting final extent of ischemic infarction using artificial neural network analysis... 22117499 - Emerging role of whole-body 18f-fluorodeoxyglucose positron emission tomography as a ma... 20880779 - Diffusion-weighted magnetic resonance imaging for tumour response assessment: why, when... 17605689 - Mr-guided focused ultrasound. 19205699 - Head and neck squamous cell carcinoma (hnscc)--detection of synchronous primaries with ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-20 |
Journal Detail:
|
Title: Skeletal radiology Volume: - ISSN: 1432-2161 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7701953 Medline TA: Skeletal Radiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Synergy Radiology Associates, P.A., 7026 Old Katy Road, #276, Houston, TX, 77024, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Partial least squares regression, support vector machine regression, and transcriptome-based distanc...
Next Document: Rosiglitazone decreases fasting plasma peptide YY(3-36) in type 2 diabetic women: a possible role in...