| Mass fragmentographic determination of gamma-aminobutyric acid and glutamic acid in discrete amygdaloid nuclei of rat brain. | |
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MedLine Citation:
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PMID: 2883258 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A mass fragmentographic method for the simultaneous quantification of gamma-aminobutyric acid (GABA) and glutamic acid is described. In a convenient one-step reaction, the two amino acids were derivatized with pentafluoropropionic anhydride and pentafluoropropanol. The derivatization products were stable for several days. The technique has been applied to the assay of GABA and Glu in five amygdaloid nuclei of the rat brain. The GABA level was high in the central and medial nuclei, whereas the Glu level was high in the lateral and basal nuclei. The regional distribution of GABA was different from that of Glu within the amygdaloid nuclei. |
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Authors:
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K Nakamura; T Matsumoto; M Hirano; H Kagoshima; T Kuroki; H Yao; H Uchimura; T Nakahara |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurochemistry Volume: 48 ISSN: 0022-3042 ISO Abbreviation: J. Neurochem. Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1987-06-25 Completed Date: 1987-06-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985190R Medline TA: J Neurochem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1842-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amygdala
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analysis* Animals Gas Chromatography-Mass Spectrometry Glutamates / analysis* Glutamic Acid Male Rats Rats, Inbred Strains gamma-Aminobutyric Acid / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Glutamates; 56-12-2/gamma-Aminobutyric Acid; 56-86-0/Glutamic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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