Document Detail


Mass Spectrometry Parameters Optimization for the 46 Multiclass Pesticides Determination in Strawberries with Gas Chromatography Ion-Trap Tandem Mass Spectrometry.
MedLine Citation:
PMID:  22993048     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Multiclass analysis method was optimized in order to analyze pesticides traces by gas chromatography with ion-trap and tandem mass spectrometry (GC-MS/MS). The influence of some analytical parameters on pesticide signal response was explored. Five ion trap mass spectrometry (IT-MS) operating parameters, including isolation time (IT), excitation voltage (EV), excitation time (ET), maximum excitation energy or "q" value (q), and isolation mass window (IMW) were numerically tested in order to maximize the instrument analytical signal response. For this, multiple linear regression was used in data analysis to evaluate the influence of the five parameters on the analytical response in the ion trap mass spectrometer and to predict its response. The assessment of the five parameters based on the regression equations substantially increased the sensitivity of IT-MS/MS in the MS/MS mode. The results obtained show that for most of the pesticides, these parameters have a strong influence on both signal response and detection limit. Using the optimized method, a multiclass pesticide analysis was performed for 46 pesticides in a strawberry matrix. Levels higher than the limit established for strawberries by the European Union were found in some samples.
Authors:
Virgínia C Fernandes; Jose L Vera; Valentina F Domingues; Luís M S Silva; Nuno Mateus; Cristina Delerue-Matos
Related Documents :
11572388 - Prediction of internal standards in reversed-phase liquid chromatography. 1. initial st...
20135708 - 2-d rp/rplc method to separate components in fructus schisandrae chinensis.
10726878 - Selection of mobile phase in high-performance liquid chromatographic determination for ...
11849918 - Evaluation of the human serum albumin column as a discovery screening tool for plasma p...
23436398 - Theoretical tools for predicting optimal cross-sectional shapes in micro gas chromatogr...
21383448 - Impact of sampling procedures on the results of breath analysis.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-20
Journal Detail:
Title:  Journal of the American Society for Mass Spectrometry     Volume:  -     ISSN:  1879-1123     ISO Abbreviation:  J. Am. Soc. Mass Spectrom.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010412     Medline TA:  J Am Soc Mass Spectrom     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Requimte, Instituto Superior de Engenharia, Instituto Politécnico do Porto, Rua Dr António Bernardino de Almeida, 431, 4200-072, Porto, Portugal.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Minimizing Carry-Over in an Online Pepsin Digestion System used for the H/D Exchange Mass Spectromet...
Next Document:  Modulation of nociception by social factors in rodents: contribution of the opioid system.