Document Detail


Masked hypertension defined by ambulatory blood pressure monitoring is associated with an increased serum glucose level and urinary albumin-creatinine ratio.
MedLine Citation:
PMID:  20695934     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors evaluated the relationship of hypertensive target organ damage to masked hypertension assessed by ambulatory blood pressure (BP) and home blood pressure (HBP) monitoring in 129 participants without taking antihypertensive medication. Masked hypertension was defined as office BP < or =140/90 mm Hg and 24-hour ambulatory BP > or =130/80 mm Hg. The masked hypertensive participants defined by 24-hour ambulatory BP (n=13) had a higher serum glucose level (126 vs 96 mg/dL, P=.001) and urinary albumin-creatinine ratio (38.0 vs 7.5 mg/gCr, P<.001) than the normotensive participants (n=74); however, these relationships were not observed when the authors defined groups using HBP (> or =135/85 mm Hg). Masked hypertension by both 24-hour ambulatory BP and HBP had a higher urinary albumin-creatinine ratio than normotension by both 24-hour ambulatory BP and HBP (62.1 vs 7.4 mg/gCr, P=.001), and than masked hypertension by HBP alone (9.3 mg/gCr, P=.009). Masked hypertension defined by 24-hour ambulatory BP is associated with an increased serum glucose level and urinary albumin-creatinine ratio, but these relationships are not observed in masked hypertension defined by HBP.
Authors:
Joji Ishikawa; Satoshi Hoshide; Kazuo Eguchi; Joseph E Schwartz; Thomas G Pickering; Kazuyuki Shimada; Kazuomi Kario
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  12     ISSN:  1751-7176     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-10     Completed Date:  2010-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  578-87     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University, School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan. george@jichi.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Albuminuria / urine*
Blood Glucose / metabolism*
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory*
Circadian Rhythm / physiology
Creatinine / urine*
Cross-Sectional Studies
Female
Humans
Hypertension / epidemiology,  metabolism*,  physiopathology*
Male
Middle Aged
Office Visits
Prevalence
Chemical
Reg. No./Substance:
0/Blood Glucose; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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