| Masimo Rad-57 Pulse CO-Oximeter for noninvasive carboxyhemoglobin measurement. | |
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MedLine Citation:
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PMID: 19298159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Noninvasive methods of body fluid chemical measurement have been expanding. New technologies are enabling the quantification of different compounds in the blood and interstitial tissues. One example of this is the pulse oximeter, which has facilitated the measurement of oxyhemoglobin rapidly and reliably without the requirement of blood-draws. The Masimo Rad-57 Pulse CO-Oximeter expanded the capabilities of pulse-oximetry to include measurements of carboxyhemoglobin and methemoglobin. This innovation has revolutionized the paradigm for detection of patients with CO poisoning. Previously, clinicians relied on historical information and patient signs and symptoms pointing to the possibility of CO exposure or toxicity. Only then would a blood test be ordered to measure carboxyhemoglobin levels. Since the presentation of CO poisoning is nonspecific and overlaps with many other conditions, and since the presence of environmental CO is often unknown, the detection of this condition was only possible in cases where the presence of CO was obvious or where the symptoms were severe. We now know, from studies conducted using the Rad-57, the only US FDA-approved device for noninvasive measurement of SpCO, that there are a significant number of patients who experience CO exposure but are nonsymptomatic. The Rad-57 provides a clinical justification for screening in the healthcare setting to identify patients with significant CO exposure who would otherwise be undetected. |
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Authors:
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Selim Suner; John McMurdy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of medical devices Volume: 6 ISSN: 1745-2422 ISO Abbreviation: - Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-03-20 Completed Date: 2009-06-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230445 Medline TA: Expert Rev Med Devices Country: England |
Other Details:
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Languages: eng Pagination: 125-30 Citation Subset: IM |
Affiliation:
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Brown University, Disaster Medicine and Emergency Preparedness, Department of Emergency Medicine, USA. ssuner@brown.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carboxyhemoglobin
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analysis* Clinical Trials as Topic Emergency Service, Hospital Humans Oximetry / instrumentation* Rhode Island Spectrum Analysis |
| Chemical | |
Reg. No./Substance:
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9061-29-4/Carboxyhemoglobin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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