Document Detail


Marked improvement of Churg-Strauss vasculitis with intravenous gamma globulins during pregnancy.
MedLine Citation:
PMID:  17486292     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Churg-Strauss syndrome (CSS) is an extremely rare disease, and even less common in women of childbearing age. Patients with severe disease or those who are un-responsive to corticosteroids are usually treated with cytotoxic drugs, especially cyclophosphmide. Intravenous immunoglobulin (IVIg) has became a promising, but not completely accepted, form of treatment for systemic vasculitis that is un-responsive to standard therapy. We report a case of a woman who presented with a CSS flare during pregnancy. Because of mono-neuritis, treatment with IVIg was instituted with successful results. Our case not only supports the beneficial effect of IVIg in CSS, but it also illustrates its successful and safe use in a patient who was pregnant. We discuss the indication of IVIg during the course of anti-neutrophil cytoplasm antigen (ANCA) vasculitis during the pregnancy.
Authors:
Arnaud Hot; Laurent Perard; Brigitte Coppere; Marie Simon; Françoise Bouhour; Jacques Ninet
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-05-08
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-09     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  2149-51     Citation Subset:  IM    
Affiliation:
Service de Medecine Interne, Hôpital Edouard Herriot, 3 Place Arsonval, Lyon, CEDEX 03, 69003, France. arnaud.hot@wanadoo.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Churg-Strauss Syndrome / drug therapy*
Female
Follow-Up Studies
Humans
Immunoglobulins, Intravenous / therapeutic use*
Immunologic Factors / therapeutic use*
Pregnancy
Pregnancy Complications, Cardiovascular / drug therapy*
Pregnancy Outcome
Chemical
Reg. No./Substance:
0/Immunoglobulins, Intravenous; 0/Immunologic Factors

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