Document Detail

Marked variations in proximal colon cancer survival by race/ethnicity within the United States.
MedLine Citation:
PMID:  19996985     Owner:  NLM     Status:  MEDLINE    
GOALS: To investigate the race/ethnicity and sex-specific variations in proximal colon cancer survival within the United States.
BACKGROUND: Recent studies suggest a shift toward more proximal distributions of colon cancers. Survival benefits from screening colonoscopy may be limited to left-sided cancers. Identifying groups at greatest risk for mortality from proximal cancers will help to target health care resources to address these disparities.
STUDY: A retrospective cohort study from 1973 to 2004 using a large population-based cancer registry to investigate demographic variations in colon cancer survival.
RESULTS: Marked sex and race/ethnicity-specific variations in proximal colon cancer survival were observed. Overall 5-year survival was greatest in females (5-y survival, females: 44.5% and males: 41.7%, P<0.001) and in Asians (5-y survival, Asians: 50.4%, non-Hispanic whites: 43.1%, blacks: 39.7%, and Hispanics: 46.7%, P<0.001). Compared with females, males had significantly worse 5-year survival outcomes [odds ratios (OR), 0.77; 95% confidence intervals (CI), 0.75-0.79]. Compared with non-Hispanic whites, blacks had worse 5-year survival odds (OR, 0.74; 95% CI, 0.70-0.78) and Asians had better survival outcomes (OR, 1.16; 95% CI, 1.08-1.24).
CONCLUSIONS: There exists significant sex and race/ethnicity-specific disparities in 5-year survival from proximal colon cancer. These differences may be explained by variations in delivery of health care between demographic groups or differences in disease biology specific to each group.
Robert John Wong
Related Documents :
18260725 - Population-based cancer survival in sites in viet nam.
22639245 - Meanings of happiness among two ethnic groups living with advanced cancer in south lond...
2766215 - The survival pattern in male breast cancer. an analysis of 1429 patients from the nordi...
10070685 - Mixture models for cancer survival analysis: application to population-based data with ...
23167405 - Effect of portal vein chemotherapy on liver metastasis after surgical resection of colo...
10578485 - Plant foods, antioxidants, and prostate cancer risk: findings from case-control studies...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  44     ISSN:  1539-2031     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-17     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  625-30     Citation Subset:  IM    
Department of Medicine, California Pacific Medical Center, San Francisco, CA 94115, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cohort Studies
Colonic Neoplasms / epidemiology*,  ethnology,  pathology
Continental Population Groups / statistics & numerical data*
Healthcare Disparities / statistics & numerical data*
Middle Aged
Retrospective Studies
Sex Factors
Survival Analysis
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A randomized, double-blind, phase 3 study of fospropofol disodium for sedation during colonoscopy.
Next Document:  Octreotide bolus injection and azygos blood flow in patients with cirrhosis: is the effect really pr...