Document Detail


Marked variations in proximal colon cancer survival by race/ethnicity within the United States.
MedLine Citation:
PMID:  19996985     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
GOALS: To investigate the race/ethnicity and sex-specific variations in proximal colon cancer survival within the United States.
BACKGROUND: Recent studies suggest a shift toward more proximal distributions of colon cancers. Survival benefits from screening colonoscopy may be limited to left-sided cancers. Identifying groups at greatest risk for mortality from proximal cancers will help to target health care resources to address these disparities.
STUDY: A retrospective cohort study from 1973 to 2004 using a large population-based cancer registry to investigate demographic variations in colon cancer survival.
RESULTS: Marked sex and race/ethnicity-specific variations in proximal colon cancer survival were observed. Overall 5-year survival was greatest in females (5-y survival, females: 44.5% and males: 41.7%, P<0.001) and in Asians (5-y survival, Asians: 50.4%, non-Hispanic whites: 43.1%, blacks: 39.7%, and Hispanics: 46.7%, P<0.001). Compared with females, males had significantly worse 5-year survival outcomes [odds ratios (OR), 0.77; 95% confidence intervals (CI), 0.75-0.79]. Compared with non-Hispanic whites, blacks had worse 5-year survival odds (OR, 0.74; 95% CI, 0.70-0.78) and Asians had better survival outcomes (OR, 1.16; 95% CI, 1.08-1.24).
CONCLUSIONS: There exists significant sex and race/ethnicity-specific disparities in 5-year survival from proximal colon cancer. These differences may be explained by variations in delivery of health care between demographic groups or differences in disease biology specific to each group.
Authors:
Robert John Wong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical gastroenterology     Volume:  44     ISSN:  1539-2031     ISO Abbreviation:  J. Clin. Gastroenterol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-17     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910017     Medline TA:  J Clin Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  625-30     Citation Subset:  IM    
Affiliation:
Department of Medicine, California Pacific Medical Center, San Francisco, CA 94115, USA. RobertWong123@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cohort Studies
Colonic Neoplasms / epidemiology*,  ethnology,  pathology
Continental Population Groups / statistics & numerical data*
Female
Healthcare Disparities / statistics & numerical data*
Humans
Male
Middle Aged
Registries
Retrospective Studies
Sex Factors
Survival Analysis
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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