Document Detail

Marine genomics: at the interface of marine microbial ecology and biodiscovery.
MedLine Citation:
PMID:  20953417     Owner:  NLM     Status:  MEDLINE    
The composition and activities of microbes from diverse habitats have been the focus of intense research during the past decade with this research being spurred on largely by advances in molecular biology and genomic technologies. In recent years environmental microbiology has entered very firmly into the age of the 'omics' – (meta)genomics, proteomics, metabolomics, transcriptomics – with probably others on the rise. Microbes are essential participants in all biogeochemical processes on our planet, and the practical applications of what we are learning from the use of molecular approaches has altered how we view biological systems. In addition, there is considerable potential to use information about uncultured microbes in biodiscovery research as microbes provide a rich source of discovery for novel genes, enzymes and metabolic pathways. This review explores the brief history of genomic and metagenomic approaches to study environmental microbial assemblages and describes some of the future challenges involved in broadening our approaches – leading to new insights for understanding environmental problems and enabling biodiscovery research.
Karla B Heidelberg; Jack A Gilbert; Ian Joint
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Publication Detail:
Type:  Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  Microbial biotechnology     Volume:  3     ISSN:  1751-7915     ISO Abbreviation:  Microb Biotechnol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-02-16     Completed Date:  2011-05-02     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  101316335     Medline TA:  Microb Biotechnol     Country:  England    
Other Details:
Languages:  eng     Pagination:  531-43     Citation Subset:  IM    
Department of Biological Sciences, University of Southern California, 3616 Trousdale Parkway, Los Angeles, CA 90089-0371, USA.
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MeSH Terms
Aquatic Organisms / classification,  genetics*,  isolation & purification*,  metabolism
Biotechnology / trends
Genomics* / history
History, 20th Century
History, 21st Century
Marine Biology* / history
Seawater / microbiology,  virology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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