Document Detail

Marine cyanobacterial fatty acid amides acting on cannabinoid receptors.
MedLine Citation:
PMID:  23143757     Owner:  NLM     Status:  MEDLINE    
Striking cAMP: certain fatty acid amides from marine cyanobacteria can mimic the endocannabinoids. Serinolamide B, a new analogue identified from a Guamanian sample, and malyngamide B, a representative member of a large class of cyanobacterial metabolites, can decrease forskolin-induced cAMP accumulation through the cannabinoid receptors.
Rana Montaser; Valerie J Paul; Hendrik Luesch
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-11-09
Journal Detail:
Title:  Chembiochem : a European journal of chemical biology     Volume:  13     ISSN:  1439-7633     ISO Abbreviation:  Chembiochem     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  2013-06-10     Revised Date:  2014-01-10    
Medline Journal Info:
Nlm Unique ID:  100937360     Medline TA:  Chembiochem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2676-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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MeSH Terms
Amides / chemistry*
Aquatic Organisms / chemistry*
Biomimetic Materials / chemistry,  pharmacology
Cannabinoid Receptor Agonists / chemistry,  pharmacology
Cannabinoid Receptor Antagonists / chemistry,  pharmacology
Cell Survival / drug effects
Cyanobacteria / chemistry*
Fatty Acids / chemistry*,  pharmacology*
HT29 Cells
MCF-7 Cells
Receptors, Cannabinoid / metabolism*
Grant Support
P41 GM086210/GM/NIGMS NIH HHS; P41M086210//PHS HHS
Reg. No./Substance:
0/Amides; 0/Cannabinoid Receptor Agonists; 0/Cannabinoid Receptor Antagonists; 0/Fatty Acids; 0/Receptors, Cannabinoid

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