Document Detail


Marijuana as a trigger of cardiovascular events: speculation or scientific certainty?
MedLine Citation:
PMID:  17005273     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Marijuana is the most widely used illicit substance in the United States. Cardiovascular complications in association with marijuana use have been reported during the past three decades. In view of the elevated public interest in this drug's role in pharmacotherapy in the recent years and the aging population of long-term marijuana users from the late 1960s, encounters with marijuana-related cardiovascular adversities may be silently on the rise. The purpose of this article is to increase awareness of the potential of marijuana to lead to cardiovascular disease. Here, we will discuss the physiologic effects of marijuana and include a comprehensive review of the studies and case reports that provide supportive evidence for marijuana as a trigger of adverse cardiovascular events, including tachyarrhythmias, acute coronary syndrome, vascular complications, and even congenital heart defects.
Authors:
Arash Aryana; Mark A Williams
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-09-26
Journal Detail:
Title:  International journal of cardiology     Volume:  118     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-23     Completed Date:  2007-08-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  141-4     Citation Subset:  IM    
Affiliation:
Cardiac Arrhythmia Service, Massachusetts General Hospital, 55 Fruit Street-GRB-109, Boston, MA 02114, USA. aaryana@partners.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Angina Pectoris / chemically induced
Cannabis / adverse effects*
Cardiovascular Diseases / chemically induced*
Female
Heart Defects, Congenital / chemically induced
Humans
Male
Middle Aged
Myocardial Infarction / chemically induced
Paternal Exposure / adverse effects
Psychotropic Drugs / pharmacology
Street Drugs / adverse effects,  pharmacology
Tachycardia / chemically induced
Tetrahydrocannabinol / pharmacology
Vasoconstriction / drug effects
Chemical
Reg. No./Substance:
0/Psychotropic Drugs; 0/Street Drugs; 1972-08-3/Tetrahydrocannabinol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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