Document Detail


Marijuana and alcohol use in pregnancy.
MedLine Citation:
PMID:  6365495     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The literature is sparse on the adverse effects of moderate alcohol consumption and marijuana use during pregnancy. Recent studies have evaluated the association of these drugs of abuse with pregnancy outcome, each using interview and medical record data of over 12 000 women. Children of marijuana users were more likely to have one or more major malformations, lower birthweight, and shorter gestation than children of nonusers. However, when logistic regression was used to control for other variables, these relationships were not statistically significant. The odds ratio for major malformations does, however, remain suggestive for marijuana. The use of similar logistic regression techniques revealed that the only statistical association between alcohol intake of 14 or more drinks per week was placenta abruptio. With the exception of placenta abruptio, alcohol intake of fewer than 14 drinks weekly was not associated with an increased risk of any adverse outcome. There was no association between alcohol use at any level and the rate of congenital malformations. Recommendations based on these data are presented.
Authors:
C S Conner
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drug intelligence & clinical pharmacy     Volume:  18     ISSN:  0012-6578     ISO Abbreviation:  Drug Intell Clin Pharm     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-04-26     Completed Date:  1984-04-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0212457     Medline TA:  Drug Intell Clin Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  233-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced / etiology*
Abruptio Placentae / chemically induced
Birth Weight / drug effects
Cannabis*
Ethanol / adverse effects*
Female
Fetus / drug effects
Humans
Infant, Newborn
Pregnancy
Pregnancy Complications / chemically induced*
Risk
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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