Document Detail


Marfan syndrome in a Triple-X girl: a new association?
MedLine Citation:
PMID:  20415197     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Triple X is a sex chromosomal abnormality that involves the presence of three sex chromosomes resulting in 47, XXX karyotype. Most patients suffering from this syndrome are usually mentally normal or subnormal with no gross malformation. AIM: to report an unusual association between Triple X and Marfan disease in a girl. CASE REPORT: A case of a triple X girl with craniofacial dysmorphy and skeletal anomalies, who did feat Marfan criteria by age, is presented. CONCLUSION: To the best of our knowledge this association has never been reported. Some clinical features are common between Triple X and Marfan disease so a careful follow-up is needed and investigations should be performed in these patients because Marfan syndrome may be incomplete in early age.
Authors:
Faten Tinsa; Lotfi Karboul; Jalel Chekib; Samia Hamouda; Lamia Ben Jemaa; Khadija Boussetta; Souad Bousnina
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  La Tunisie m?dicale     Volume:  88     ISSN:  0041-4131     ISO Abbreviation:  Tunis Med     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413766     Medline TA:  Tunis Med     Country:  Tunisia    
Other Details:
Languages:  eng     Pagination:  203-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics B, Children's Hospital of Tunis.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple
Atrophy / radiography
Brain / pathology
Chromosomes, Human, X / genetics*
Consanguinity
Female
Humans
Infant
Marfan Syndrome / genetics*
Sex Chromosome Aberrations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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