Document Detail

Mapping of vertebral artery perfusion territories using arterial spin labeling MRI.
MedLine Citation:
PMID:  18777538     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To demonstrate the use of a noninvasive arterial spin labeling (ASL) MRI technique and evaluate vertebral artery (VA) territories in the brain. MATERIALS AND METHODS: Vessel-encoded ASL was used to determine the territories of the left and right VAs in five healthy subjects. Territory maps were analyzed quantitatively by comparing the fractional contributions of the left and right VAs in selected regions of interest within the brain. RESULTS: VA territory maps demonstrated a complicated pattern of perfusion to the posterior aspect of the brain, but were consistent with the posterior cerebral and cerebellar artery distributions. Cerebellar perfusion was predominantly ipsilateral (P<0.01). The total left and right VA contributions were unequal (P<0.01), and there was relatively little mixing in the vertebrobasilar system. CONCLUSION: Vessel-encoded ASL can reveal individual VA territories in the brain. In a small sample of healthy volunteers the VAs appeared to contribute unequally, provide predominantly ipsilateral supply to the cerebellum, and undergo minimal mixing in the basilar artery.
Akash P Kansagra; Eric C Wong
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  28     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-15     Completed Date:  2008-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  762-6     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2008 Wiley-Liss, Inc.
School of Medicine, University of California, San Diego, California, USA.
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MeSH Terms
Blood Flow Velocity / physiology*
Cerebrovascular Circulation / physiology*
Magnetic Resonance Imaging / methods*
Perfusion Imaging / methods*
Spin Labels
Vertebral Artery / anatomy & histology*,  physiology*
Young Adult
Grant Support
Reg. No./Substance:
0/Spin Labels

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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