Document Detail

Mapping of local cerebral blood flow with stable xenon-enhanced CT and the curve-fitting method of analysis.
MedLine Citation:
PMID:  3380959     Owner:  NLM     Status:  MEDLINE    
A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.
H Touho; J Karasawa; J Nakagawara; T Tazawa; K Yamada; Y Kuriyama; M Asai; M Kagawa; K Kobayashi; H Yasue
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  168     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-07-21     Completed Date:  1988-07-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  207-12     Citation Subset:  AIM; IM    
Department of Neurosurgery, Osaka Neurological Institute, Japan.
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MeSH Terms
Brain Injuries / radiography
Cerebral Infarction / radiography
Cerebrovascular Circulation*
Middle Aged
Tomography, X-Ray Computed / methods*
Xenon Radioisotopes / diagnostic use*
Reg. No./Substance:
0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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