Document Detail


Mapping of haploid expressed genes: genes for both mouse protamines are located on chromosome 16.
MedLine Citation:
PMID:  3008352     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mouse spermatozoa contain two protamines with different amino acid sequences. By hybridizing Southern blots of a series of mouse-hamster somatic cell hybrids containing subsets of mouse chromosomes and a complete set of hamster chromosomes with 32P-labeled cDNAs for each mouse protamine, we assign the two mouse protamine genes to chromosome 16. This report presents the first evidence for chromosomal linkage of two sperm-specific, haploid regulated gene products.
Authors:
N B Hecht; K C Kleene; P C Yelick; P A Johnson; D D Pravtcheva; F H Ruddle
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Somatic cell and molecular genetics     Volume:  12     ISSN:  0740-7750     ISO Abbreviation:  Somat. Cell Mol. Genet.     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-05-07     Completed Date:  1986-05-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8403568     Medline TA:  Somat Cell Mol Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  203-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Line
Chromosome Mapping
Cricetinae
Cricetulus
DNA Restriction Enzymes
Evolution
Genes*
Haploidy*
Humans
Hybrid Cells / cytology
Liver / metabolism
Male
Nucleic Acid Hybridization
Protamines / genetics*
Spermatozoa / metabolism
Grant Support
ID/Acronym/Agency:
GM 29224/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Protamines; EC 3.1.21.-/DNA Restriction Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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