| Mapping QTL for growth and shank traits in chickens divergently selected for high or low body weight. | |
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MedLine Citation:
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PMID: 20096032 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An F(2) population (695 individuals) was established from broiler chickens divergently selected for either high (HG) or low (LG) growth, and used to localize QTL for developmental changes in body weight (BW), shank length (SL9) and shank diameter (SD9) at 9 weeks. QTL mapping revealed three genome-wide QTL on chromosomes (GGA) 2, 4 and 26 and three suggestive QTL on GGA 1, 3 and 5. Most of the BW QTL individually explained 2-5% of the phenotypic variance. The BW QTL on GGA2 explained about 7% of BW from 3 to 7 weeks of age, while that on GGA4 explained 15% of BW from 5 to 9 weeks. The BW QTL on GGA2 and GGA4 could be associated with early and late growth respectively. The GGA4 QTL also had the largest effect on SL9 and SD9 and explained 7% and 10% of their phenotypic variances respectively. However, when SL9 and SD9 were corrected with BW9, a shank length percent QTL was identified on GGA2. We identified novel QTL and also confirmed previously identified loci in other chicken populations. As the foundation population was established from commercial broiler strains, it is possible that QTL identified in this study could still be segregating in commercial strains. |
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Authors:
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G A Ankra-Badu; E Le Bihan-Duval; S Mignon-Grasteau; F Pitel; C Beaumont; M J Duclos; J Simon; W Carré; T E Porter; A Vignal; L A Cogburn; S E Aggrey |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-01-20 |
Journal Detail:
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Title: Animal genetics Volume: 41 ISSN: 1365-2052 ISO Abbreviation: Anim. Genet. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-09-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8605704 Medline TA: Anim Genet Country: England |
Other Details:
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Languages: eng Pagination: 400-5 Citation Subset: IM |
Affiliation:
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Poultry Genetics and Biotechnology Laboratory, Department of Poultry Science, and Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight* Chickens / anatomy & histology, genetics*, growth & development Chromosomes Female Genetic Variation* Genome-Wide Association Study Lower Extremity / anatomy & histology* Male Quantitative Trait Loci* Selection, Genetic* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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