| Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine. | |
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MedLine Citation:
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PMID: 1254134 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pyloric sphincter pressure was assessed with water-perfused polyvinyl tubes. Smoking one cigarette significantly decreased the basal pyloric pressure, whereas 10 mg of metoclopramide as an intravenous bolus increased the pyloric pressure in normal subjects and in patients with gastric ulcer with low basal pressure. Duodenal acidification with 0.1 N HCl significantly increased pyloric pressure. Atropine 15 mug per kg, subcutaneously prevented the rise of pyloric pressure in response to acid infusion into the duodenum. |
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Authors:
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J E Valenzuela; C Defilippi; A Csendes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gastroenterology Volume: 70 ISSN: 0016-5085 ISO Abbreviation: Gastroenterology Publication Date: 1976 Apr |
Date Detail:
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Created Date: 1976-05-18 Completed Date: 1976-05-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 481-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atropine / pharmacology* Gastrointestinal Motility / drug effects* Humans Hydrochloric Acid / diagnostic use Intubation, Gastrointestinal Manometry / instrumentation, methods Metoclopramide / pharmacology* Middle Aged Pressure Pylorus / physiology* Smoking / physiopathology* Stomach Ulcer / physiopathology |
| Chemical | |
Reg. No./Substance:
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364-62-5/Metoclopramide; 51-55-8/Atropine; 7647-01-0/Hydrochloric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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