Document Detail

Manometric characterization of rectal dysfunction following radical hysterectomy.
MedLine Citation:
PMID:  1894168     Owner:  NLM     Status:  MEDLINE    
Bladder dysfunction thought to be due to partial denervation has been described following radical hysterectomy. Some patients experience acute and chronic rectal dysfunction characterized by difficulty with defecation and loss of defecatory urge. To define this abnormality, anorectal pressure profiles were examined in 15 patients with Stage I carcinoma of the cervix before and after radical hysterectomy. Profiles were done using standard anorectal manometry with a water-infused system. In all patients preoperative manometric profiles were normal; postoperative studies were abnormal in all patients. Features seen include altered relaxation of the internal sphincter, increased distension needed to trigger relaxation, and decreased rectal sensation; external sphincters and resting internal sphincters were unchanged. Postoperatively, 12 patients reported problems with rectal function. A physiologic defect is definable in patients undergoing radical hysterectomy; this suggests disruption of the spinal reflex arcs controlling rectal emptying. These physiologic abnormalities correlate with the clinical symptomatology experienced by some patients. Continuing definition and evaluation of management options in this situation should be useful in developing effective therapy for rectal dysfunction following radical hysterectomy.
W Barnes; S Waggoner; G Delgado; K Maher; R Potkul; J Barter; S Benjamin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic oncology     Volume:  42     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-10-24     Completed Date:  1991-10-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  116-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, D.C. 20007.
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MeSH Terms
Hysterectomy / adverse effects*
Rectal Diseases / etiology*,  physiopathology
Rectum / physiopathology
Uterine Cervical Neoplasms / surgery
Comment In:
Gynecol Oncol. 1991 Aug;42(2):114-5   [PMID:  1894167 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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