Document Detail


Manometric characteristics of the upper esophageal sphincter recorded with a microsleeve.
MedLine Citation:
PMID:  11379603     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: We compared manometric recordings of the upper esophageal sphincter (UES) recorded with a miniature sleeve to those obtained using standard manometry. METHODS: The UES pressure of eight volunteer subjects was measured by station pull-through (SPT), by rapid pull-through (RPT), and with a microsleeve sensor for 30 min, followed by 15 min of esophageal acid infusion. Deglutitive UES relaxation recorded with a microsleeve and solid state sensor were compared. RESULTS: The UES pressure recorded with the microsleeve (25+/-9 mm Hg) was significantly less than that by SPT (114+/-18 mm Hg) or RPT (152+/-19 mm Hg), and was unaffected by acid infusion. Periods of low UES pressure were observed during long interswallow intervals (11+/-4, range 6-18 mm Hg). Deglutitive relaxation duration and intrabolus pressure measured with the microsleeve were less than those recorded by the solid state transducer. CONCLUSIONS: "Normal" UES pressure is heavily dependent on measurement technique; pressures obtained with a miniature sleeve are a fraction of those obtained by SPT or RPT. During periods of relative comfort with minimal swallowing, UES tone is approximately 10 mm Hg, similar to that during sleep. Volume modulation of deglutitive UES relaxation is demonstrable with a microsleeve, albeit with less precision than with a solid-state transducer.
Authors:
C Dire; G Shi; M Manka; P J Kahrilas
Related Documents :
7656753 - Physiology of ileal pouch-anal anastomosis. current concepts.
11819533 - Dynamic and ultrastructural study of sphincter of oddi in early-stage cholelithiasis in...
471153 - Comparative effects of ticrynafen and hydrochlorothiazide on blood pressure, renal func...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  96     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-25     Completed Date:  2001-06-28     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1383-9     Citation Subset:  IM    
Affiliation:
Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611-3008, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acids / pharmacology
Adult
Deglutition
Equipment Design
Esophagogastric Junction / drug effects,  physiology*
Esophagus / drug effects
Female
Humans
Male
Manometry* / instrumentation
Middle Aged
Muscle Relaxation
Perfusion
Pressure
Time Factors
Transducers
Grant Support
ID/Acronym/Agency:
R01 DC00646/DC/NIDCD NIH HHS
Chemical
Reg. No./Substance:
0/Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bond strength of binary titanium alloys to porcelain.
Next Document:  Adjuvant interferon alpha 2b in high risk melanoma - the Scottish study.