Document Detail

Mannan-binding lectin concentration during normal human pregnancy.
MedLine Citation:
PMID:  10739846     Owner:  NLM     Status:  MEDLINE    
Relative deficiency of mannan-binding lectin (MBL) is associated with recurrent miscarriage. To investigate whether MBL concentration alters as a result of pregnancy, serial measurements were made in 14 patients before and during normal early pregnancy. Additionally, a longitudinal study was made of one individual over several years and including two normal pregnancies. Three (20%) subjects experienced a significant increase in MBL concentration during pregnancy. It was concluded that a modest but significant increase in MBL concentration can result from pregnancy, but it is a rare occurrence in the first trimester.
D C Kilpatrick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  15     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-05     Completed Date:  2000-05-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  941-3     Citation Subset:  IM    
Academic Unit, Department of Transfusion Medicine, 2 Forrest Road, Edinburgh EH1 2QN, UK.
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MeSH Terms
Abortion, Habitual / blood,  therapy
Carrier Proteins / blood*
Leukocytes / immunology
Reg. No./Substance:
0/Carrier Proteins; 0/Collectins

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