Document Detail


Manipulation of the functional activity of the gut by dietary and other means (antibiotics/probiotics) in ruminants.
MedLine Citation:
PMID:  2191095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mucosa of the gut is some of the most metabolically active tissue in the body. This paper discusses the methodology used to assess enterocyte cell metabolism and nutrient uptake in the reticulorumen and small intestine of ruminant species. Metabolism of volatile fatty acids and glucose by this tissue may limit the availability of essential nutrients to peripheral tissues, and the extent to which this may vary between concentrate-based and forage-based diets is discussed. Factors that affect the development and expression of metabolite uptake by the enterocyte are considered in addition to the influence that manipulation of the microbial flora of the gut by the use of antibiotic growth promoters or probiotics may have upon this process. Data are presented to show that the use of antibiotic compounds in ruminant feeds can influence the rate of cell turnover in the small intestine and the rate of glucose uptake by isolated brush border vesicles.
Authors:
D S Parker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of nutrition     Volume:  120     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-07-19     Completed Date:  1990-07-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  639-48     Citation Subset:  IM    
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Animal Nutritional Physiological Phenomena*
Animals
Anti-Bacterial Agents / administration & dosage,  pharmacology*
Glucose / metabolism
Intestinal Mucosa / drug effects,  metabolism
Intestines / drug effects*,  metabolism
Ruminants / metabolism*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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