Document Detail


Manifestation late in life of idiopathic adulthood ductopenia.
MedLine Citation:
PMID:  8544645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic adulthood ductopenia is a chronic cholestasic liver disease of unknown etiology characterized by the loss of interlobular bile ducts. We describe three patients who fulfilled the diagnostic criteria of idiopathic adulthood ductopenia, but differed from the cases reported so far in late manifestation of the disease and a benign clinical course despite histologic evidence of ongoing cholangitis. Treatment with ursodeoxycholic acid in one patient resulted in improvement of biochemical markers of cholestasis, suggesting that chronic cholestasis in idiopathic adulthood ductopenia can be influenced beneficially.
Authors:
C Müller; W Ulrich; E Penner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Liver     Volume:  15     ISSN:  0106-9543     ISO Abbreviation:  Liver     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1996-02-13     Completed Date:  1996-02-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8200939     Medline TA:  Liver     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  213-8     Citation Subset:  IM    
Affiliation:
Universitätsklinik für Innere Medizin IV, Abteilung Gastroenterologie und Hepatologie, Vienna, Austria.
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MeSH Terms
Descriptor/Qualifier:
Aged
Bile Ducts, Intrahepatic / pathology*
Cholestasis, Intrahepatic / drug therapy,  pathology,  physiopathology*
Female
Humans
Male
Middle Aged
Ursodeoxycholic Acid / therapeutic use
Chemical
Reg. No./Substance:
128-13-2/Ursodeoxycholic Acid

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