Document Detail


Mania: psychiatric manifestations of the antiphospholipid syndrome.
MedLine Citation:
PMID:  18794513     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Antiphospholipid syndrome (APS) is a prothrombotic condition characterized by recurrent vascular thrombosis and/or pregnancy morbidity in the presence of circulating antiphospholipid antibodies. Central nervous system (CNS) involvement is a prominent feature of APS, and many neurological manifestations have been described in published reports. There are limited data on psychiatric syndromes occurring in association with APS, and there have been no previous reports of mania associated with APS. METHOD: The authors present the case of a 31-year-old man who experienced an acute manic episode in association with APS. They review the literature on psychiatric manifestations of APS, discuss potential mechanisms of CNS pathogenesis, and consider diagnostic and treatment implications of the co-occurrence of APS and psychiatric symptoms.
Authors:
Haniya Raza; Steven A Epstein; Maryland Pao; Donald L Rosenstein
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Psychosomatics     Volume:  49     ISSN:  1545-7206     ISO Abbreviation:  Psychosomatics     Publication Date:    2008 Sep-Oct
Date Detail:
Created Date:  2008-09-16     Completed Date:  2009-05-08     Revised Date:  2012-03-07    
Medline Journal Info:
Nlm Unique ID:  0376506     Medline TA:  Psychosomatics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  438-41     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Georgetown University Hospital, Washington, DC, USA. haniyaraza@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiphospholipid Syndrome* / diagnosis,  physiopathology,  psychology
Antipsychotic Agents / therapeutic use
Benzodiazepines / therapeutic use
Bipolar Disorder / diagnosis*,  drug therapy,  psychology*
Brain / physiopathology
Diagnosis, Differential
Haloperidol / therapeutic use
Humans
Lithium Compounds / therapeutic use
Male
Grant Support
ID/Acronym/Agency:
Z99 MH999999/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Antipsychotic Agents; 0/Lithium Compounds; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 52-86-8/Haloperidol
Comments/Corrections

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