| Manganese-Induced Parkinsonism due to Ephedrone Abuse. | |
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MedLine Citation:
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PMID: 21403909 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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During recent years, a syndrome of hypokinesia, dysarthria, dystonia, and postural impairment, related to intravenous use of a "designer" psychostimulant derived from pseudoephedrine using potassium permanganate as the oxidant, has been observed in drug addicts in several countries in Eastern Europe with some cases also in Western countries. A levodopa unresponsive Parkinsonian syndrome occurs within a few months of abusing the homemade drug mixture containing ephedrone (methcathinone) and manganese. The development of this neurological syndrome has been attributed to toxic effects of manganese, but the role of the psychostimulant ephedrone is unclear. This paper describes the clinical syndrome, results of neuroimaging, and therapeutic attempts. |
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Authors:
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Katrin Sikk; Sulev Haldre; Sten-Magnus Aquilonius; Pille Taba |
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Publication Detail:
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Type: Journal Article Date: 2011-02-17 |
Journal Detail:
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Title: Parkinson's disease Volume: 2011 ISSN: 2042-0080 ISO Abbreviation: Parkinsons Dis Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-15 Completed Date: 2011-07-14 Revised Date: 2011-07-26 |
Medline Journal Info:
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Nlm Unique ID: 101539877 Medline TA: Parkinsons Dis Country: England |
Other Details:
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Languages: eng Pagination: 865319 Citation Subset: - |
Affiliation:
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Department of Neurology and Neurosurgery, University of Tartu, L. Puusepa 8, 51014 Tartu, Estonia. |
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