Document Detail


Managing contraception and pregnancy in the rheumatologic diseases.
MedLine Citation:
PMID:  20534371     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Most pregnancies in women with rheumatologic disease will result in the delivery of a healthy baby. Pregnancy can be particularly risky in women with active disease or on teratogenic medications, making contraception an important issue for these women. All women with rheumatologic disease have contraceptive options, including barrier methods, the intra-uterine device and progesterone-only medications. Active inflammatory disease, whether in the form of lupus, systemic vasculitis or myositis, places the pregnancy at increased risk. Pre-eclampsia is a particular risk for women with lupus or antiphospholipid syndrome and may be decreased by daily low-dose aspirin. Rheumatoid arthritis typically improves and does not have a major impact on pregnancy outcomes. The expected post-partum arthritis flare may be avoided by restarting medications soon after delivery. Judicious use of medication and close observation may be the keys to successful pregnancy in women with rheumatologic disease.
Authors:
Megan E B Clowse
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical rheumatology     Volume:  24     ISSN:  1532-1770     ISO Abbreviation:  Best Pract Res Clin Rheumatol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-10     Completed Date:  2010-09-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121149     Medline TA:  Best Pract Res Clin Rheumatol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  373-85     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Rheumatology & Immunology Duke University Health System, Durham, UK. Megan.clowse@duke.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiphospholipid Syndrome / complications,  drug therapy
Antirheumatic Agents / therapeutic use
Arthritis, Rheumatoid / complications,  drug therapy
Contraception / methods*
Female
Humans
Lupus Erythematosus, Systemic / complications,  drug therapy
Myositis / complications,  drug therapy
Pregnancy
Pregnancy Complications*
Pregnancy Outcome*
Rheumatic Diseases / complications*,  diagnosis,  drug therapy
Scleroderma, Limited / complications,  drug therapy
Vasculitis / complications,  drug therapy
Chemical
Reg. No./Substance:
0/Antirheumatic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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