Document Detail


Managing endometriosis-associated infertility.
MedLine Citation:
PMID:  22031261     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endometriosis is associated with infertility; however, the etiology of this association is unclear, thus complicating management. Several mechanisms of pathogenesis have been proposed; however, no one theory has been implicated. Medical therapy can be helpful in managing symptoms, but does not improve pregnancy rates. The role of surgical treatment remains controversial. There is little data regarding ovulation induction treatments for endometriosis only, whereas superovulation with intrauterine insemination has shown modest improvement in pregnancy rates in women who may have endometriosis. The most effective treatment for endometriosis-associated infertility is in vitro fertilization. Recent focus on proteomics and genetics of the disease may aid in optimizing treatment options.
Authors:
Suneeta Senapati; Kurt Barnhart
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  54     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-10-27     Completed Date:  2012-03-29     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  720-6     Citation Subset:  IM    
Affiliation:
Reproductive Endocrinology and Infertility, Reproductive Research Unit, Women's Heath Clinical Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Suneeta.Senapati@uphs.upenn.edu
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MeSH Terms
Descriptor/Qualifier:
Endometriosis / complications*,  drug therapy,  surgery
Female
Fertilization in Vitro
Humans
Infertility, Female / etiology*,  therapy*
Ovulation Induction
Pregnancy
Pregnancy Rate
Uterine Diseases / complications*
Grant Support
ID/Acronym/Agency:
K24 HD060687/HD/NICHD NIH HHS; T32 HD007440/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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