Document Detail


Management of unstable angina and non-ST-segment elevation myocardial infarction.
MedLine Citation:
PMID:  11480381     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Most of the patients with acute coronary syndromes present with unstable angina or non-ST-segment elevation myocardial infarction. Recent advances in the diagnosis and treatment of these conditions have changed the management guidelines, allowing for better patient care. The purpose of this review is to summarize the current knowledge and present both established and new or evolving strategies used in the treatment of patients with unstable angina and non-ST-segment elevation myocardial infarction. Use of aspirin, nitrates, beta-blockers, calcium channel blockers, and anticoagulation with unfractionated heparin has been a common practice in these patients. While still effective and recommended, the emergence of new anticoagulants (low molecular weight heparins) and antiplatelet agents (ADP inhibitors and glycoprotein IIb/IIIa blockers) has added significant benefit to the treatment options and has resulted in a better prognosis for the patients. It also appears that, in view of recent trials, an early invasive approach is becoming the standard of care, especially for high-risk patients.
Authors:
H G Hanley; T M Nylk; N Nguyen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society     Volume:  153     ISSN:  0024-6921     ISO Abbreviation:  J La State Med Soc     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-08-01     Completed Date:  2001-08-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505618     Medline TA:  J La State Med Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  306-11     Citation Subset:  IM    
Affiliation:
Cardiology Section, Louidisns State University Health Sciences Center, Department of Internal Medicine, Shreveport, Louisiana, USA.
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MeSH Terms
Descriptor/Qualifier:
Angina, Unstable / drug therapy*
Humans
Myocardial Infarction / drug therapy*
Platelet Glycoprotein GPIIb-IIIa Complex / therapeutic use
Syndrome
Chemical
Reg. No./Substance:
0/Platelet Glycoprotein GPIIb-IIIa Complex

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