| Management of treatment-associated toxicites of anti-angiogenic therapy in patients with brain tumors. | |
| | |
MedLine Citation:
|
PMID: 22307472 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Anti-angiogenic therapies, including bevacizumab, are being used with increasing frequency in the management of malignant glioma. Common clinically significant toxicities include hypertension and proteinuria, poor wound healing, and the potential for thromboembolic events. Literature related to the use of bevacizumab in malignant glioma, reported toxicities in this patient population, and management of these toxicities was reviewed. Recommendations for assessment and management are provided. Anti-angiogenic therapies will continue to have a role in the treatment of malignant glioma. Further studies of the prevention, assessment, and management of these toxicities are warranted. |
| | |
Authors:
|
Terri S Armstrong; Patrick Y Wen; Mark R Gilbert; David Schiff |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-3 |
Journal Detail:
|
Title: Neuro-oncology Volume: - ISSN: 1523-5866 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100887420 Medline TA: Neuro Oncol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Integrative Nursing Care, UTHSC-SON (T.S.A.); Department of Neuro-Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas (T.S.A., M.R.G.); Center For Neuro-Oncology, Dana-Farber Cancer Institute and Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Boston,Massachusetts (P.Y.W.); Departments of Neurology, Neurological Surgery, and Medicine (Hematology-Oncology), University of Virginia, Richmond, Virginia (D.S.). |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vessel health and preservation (Part 1): A new evidence-based approach to vascular access selection ...
Next Document: Cognitive functioning in newly presenting patients with supratentorial intracranial tumors: is there...