| Management of trauma-induced coagulopathy: trends and practices. | |
| | |
MedLine Citation:
|
PMID: 20977127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Nearly one-fourth of all trauma admissions present in varying degrees of coagulopathy. According to a US study, 40% of trauma fatalities are due to hemorrhage and hemorrhagic shock, and nearly all patients who are alive when they reach the hospital are coagulopathic when they die. Once coagulopathy develops, patient morbidity drastically increases. Because of the clinical significance of trauma-induced coagulopathy, management strategies to reduce the morbidity and mortality have recently become of interest. This article will review the pathology of trauma-induced coagulopathy and current trends in management, as well as closely examine the data surrounding the use of recombinant factor VII for the treatment of trauma-induced coagulopathy. |
| | |
Authors:
|
Matthew R D'Angelo; Richard P Dutton |
Related Documents
:
|
17987957 - The epidemiology, evaluation, and management of stingray injuries. 7328687 - Management of frostbite injuries. 19303237 - Evaluation and management of moderate to severe pediatric head trauma. 22789027 - Differences in obesity management among physicians. 19705417 - Mind-body complementary alternative medicine use and quality of life in adolescents wit... 21140617 - Managing talent for the future. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: AANA journal Volume: 78 ISSN: 0094-6354 ISO Abbreviation: AANA J Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-10-27 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0431420 Medline TA: AANA J Country: United States |
Other Details:
|
Languages: eng Pagination: 35-40 Citation Subset: N |
Affiliation:
|
R Adams Cowley Shock Trauma Center, Division of Trauma Amesthesiology, University of Maryland Medical Center, Baltimore, Maryland, USA. mdangelo@umaryland.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acidosis
/
complications Blood Coagulation Disorders / drug therapy*, etiology*, physiopathology Brain Injuries / complications Factor VIIa / therapeutic use* Fever / complications Fluid Therapy / adverse effects Humans Off-Label Use Recombinant Proteins / therapeutic use Shock, Hemorrhagic / complications Wounds and Injuries / complications* |
| Chemical | |
Reg. No./Substance:
|
0/Recombinant Proteins; 0/recombinant FVIIa; EC 3.4.21.21/Factor VIIa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nonopioid anesthesia for awake craniotomy: a case report.
Next Document: Massive hemoptysis during monitored anesthesia care for esophagogastroduodenoscopy with percutaneous...