| Management of thrombosis in peripheral arterial disease. | |
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MedLine Citation:
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PMID: 7804739 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is accumulating evidence that thrombosis contributes to peripheral arterial disease, and that antithrombotic therapy should be considered at all symptomatic stages. In claudication, antiplatelet therapy is indicated in addition to lifestyle advice and sometimes surgery or angioplasty; the place of thrombolysis is unproven. In chronic critical limb ischaemia, prophylaxis of venous thromboembolism by low-dose heparin is indicated during hospitalisation, as is long-term antiplatelet therapy; local thrombolysis or systemic prostanoid infusions are increasingly used. In acute critical limb ischaemia, full dose heparinisation is followed by thromboembolectomy, local thrombolysis, angioplasty and surgery as appropriate. Antiplatelet therapy and/or anticoagulation are employed following such procedures, according to risk factors in the individual patient. Collaboration between vascular surgeons, radiologists and physicians is important in comprehensive patient care. |
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Authors:
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G D Lowe; A W Reid; D P Leiberman |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: British medical bulletin Volume: 50 ISSN: 0007-1420 ISO Abbreviation: Br. Med. Bull. Publication Date: 1994 Oct |
Date Detail:
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Created Date: 1995-01-30 Completed Date: 1995-01-30 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0376542 Medline TA: Br Med Bull Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 923-35 Citation Subset: IM |
Affiliation:
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University Department of Medicine, Department of Radiology, Glasgow Royal Infirmary, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arm
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blood supply Humans Intermittent Claudication / drug therapy Ischemia / drug therapy Leg / blood supply Peripheral Vascular Diseases / drug therapy* Recurrence Thrombolytic Therapy / methods* Thrombosis / complications, drug therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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