Document Detail

Management and therapy of human immunodeficiency virus-infected pregnancies in maternal-fetal medicine fellowship training programs.
MedLine Citation:
PMID:  1448269     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine attitudes and practices of obstetricians in maternal-fetal medicine fellowship programs regarding the management of human immunodeficiency virus (HIV) infection and the use of zidovudine during pregnancy. METHODS: We sent a questionnaire to the directors of all 78 approved maternal-fetal medicine fellowship programs. The responses, reflecting the consensus of the staffs of each program, were obtained and tabulated. RESULTS: Although their programs annually provide care for more than 2100 pregnant women infected with HIV, less than 25% of all maternal-fetal medicine fellowship directors reported that their patients participate in multicenter studies of HIV infection complicating pregnancy. Nearly two-thirds of the infected women are excluded from such multicenter studies. More than 70% of all program directors believe that zidovudine should be offered to symptomatic pregnant women infected with HIV; one-half question whether zidovudine poses short-term fetal risks. Nevertheless, nearly half of all HIV-infected pregnant women they manage are excluded from trials of zidovudine therapy during pregnancy. CONCLUSIONS: Many HIV-infected pregnant women who receive care in clinics of maternal-fetal medicine fellowship programs are excluded from multicenter studies. Consideration should be given to creating a national registry for this important, currently unreported, clinical resource.
J H Grossman; B M Nies; J Lopez-Zeno; S L Bathgate; D M Parenti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  80     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1992-12-24     Completed Date:  1992-12-24     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  985-8     Citation Subset:  AIM; IM; X    
Division of Maternal-Fetal Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
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MeSH Terms
Clinical Trials as Topic / utilization
Fellowships and Scholarships*
HIV Infections / drug therapy*
Health Knowledge, Attitudes, Practice*
Obstetrics* / education
Perinatology / education
Pregnancy Complications, Infectious / drug therapy*
Specialty Boards
United States
Zidovudine / therapeutic use*
Reg. No./Substance:

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