Document Detail

Management of term patients with premature rupture of membranes and an unfavorable cervix.
MedLine Citation:
PMID:  1550636     Owner:  NLM     Status:  MEDLINE    
The purpose of this prospective investigation was to evaluate a protocol for management of term patients with premature rupture of membranes (PROM) and a cervix unfavorable for induction of labor (Bishop score 4 or less). Patients initially were observed for 24 to 36 hours for the spontaneous onset of labor. If spontaneous contractions did not commence, labor was induced with oxytocin. Patients subsequently were divided into three groups: 44 who had spontaneous labor, 29 who had spontaneous labor but required oxytocin augmentation, and 39 women who had oxytocin induction. Patients who entered labor spontaneously had a significantly shorter mean latent period between rupture of membranes and onset of labor (16.0 versus 26.8 and 40.7 hours), shorter mean duration of labor (7.6 versus 12.1 and 13.1 hours), and shorter mean duration of rupture of membranes (23.6 versus 39.0 and 53.8 hours). These women also had a significant decrease in the frequency of chorioamnionitis (7 versus 14 and 33%), and their infants had fewer evaluations for sepsis (25.0 versus 34.5 and 53.8%). We conclude that term patients with PROM and an unfavorable cervix who require oxytocin augmentation or induction of labor are at increased risk for intrapartum and neonatal infection compared with those who progress through labor spontaneously.
J M Guise; P Duff; J S Christian
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  9     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-04-24     Completed Date:  1992-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  56-60     Citation Subset:  IM    
Division of Maternal-Fetal Medicine, Madigan Army Medical Center, Tacoma, Washington.
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MeSH Terms
Cervix Uteri / physiology*
Chorioamnionitis / epidemiology
Endometritis / epidemiology
Fetal Membranes, Premature Rupture / therapy*
Labor, Induced*
Pregnancy Outcome / epidemiology
Prospective Studies
Risk Factors
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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