Document Detail

Management strategy for brain tumour diagnosed during pregnancy.
MedLine Citation:
PMID:  20825287     Owner:  NLM     Status:  In-Data-Review    
The occurrence of brain tumours during pregnancy is unusual, when this happen jeopardises the lives of both the mother and infant. This article aims at identifying the best medical management to be followed for a pregnant patient harbouring a brain tumour. The records of 10 patients with brain tumours diagnosed during pregnancy were retrospectively examined. The histological diagnosis revealed 3 grade 2 astrocytomas, and 1 grade 2 oligodendroglioma. All this gliomas (100%) developed dedifferentiation in the mean period of 27 months. The histology of the others tumours were 2 grade 1 meningiomas, 1 melanoma metastasis, 1 epidermoid tumour, 1 case of chemodectoma and 1 patient with a pituitary apoplexy in a non-function adenoma. There was no operative mortality in these series, and no fetal deaths were observed. Prior to craniotomy, five patients had caesarean sections, two others had vaginal deliveries. In three patients the delivery took place after the brain tumour treatment. Two patients had vaginal delivery and eight caesarean sections. The best moment to recommend the craniotomy and the neurosurgical removal of the tumour will depend of the mother's neurological condition, the tumour histological type as well as the gestational age. A multi-disciplinary approach was used to determine the optimal management for each patient.
José Carlos Lynch; Fabiano Gouvêa; João Cláudio Emmerich; Georges Kokinovrachos; Celestino Pereira; Leonardo Welling; Sara Kislanov
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Publication Detail:
Type:  Journal Article     Date:  2010-09-08
Journal Detail:
Title:  British journal of neurosurgery     Volume:  25     ISSN:  1360-046X     ISO Abbreviation:  Br J Neurosurg     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-05-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800054     Medline TA:  Br J Neurosurg     Country:  England    
Other Details:
Languages:  eng     Pagination:  225-30     Citation Subset:  IM    
Department of Neurosurgery, Servidores do Estado Hospital, Rio de Janeiro, Brazil.
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