Document Detail

Management of sickle hemoglobinopathies in pregnant patients.
MedLine Citation:
PMID:  7282804     Owner:  NLM     Status:  MEDLINE    
During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. Prophylactic exchange transfusion was not associated with improved pregnancy outcome and was associated with significant antibody formation. Exchange transfusion may best be reserved as a treatment modality when infection, crisis, or symptomatic anemia occurs in patients with a sickle hemoglobinopathy.
J M Miller; E O Horger; T C Key; E M Walker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  141     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  237-41     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Sickle Cell / complications,  therapy*
Exchange Transfusion, Whole Blood*
Fetal Monitoring
Infant, Newborn
Isoantibodies / biosynthesis
Pregnancy Complications, Hematologic / therapy*
Prenatal Care
Reg. No./Substance:

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