| Management of primary hyperparathyroidism caused by multiple gland disease. | |
| | |
MedLine Citation:
|
PMID: 1685044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Multiple gland parathyroid disease is the pathological finding in primary hyperparathyroidism (HPT) in about 10% to 20% of all patients and in approximately a third of all patients with persistent or recurrent disease. The variability of multiple gland disease spans from 2 adenomas to diffuse hyperplasia in patients with multiple endocrine neoplasia type 1. This variability calls into question the proposed common pathophysiologic background in all of these cases. As primary treatment of multiple gland primary HPT, subtotal parathyroidectomy and thymectomy or total parathyroidectomy and heterotopic autotransplantation including thymectomy can be equally advocated. Recurrent hyperparathyroidism frequently occurs in cases of diffuse parathyroid hyperplasia. This must be considered especially in patient follow up and before each surgical procedure. Thus, a defined but adaptable therapeutic regimen might prevent permanent hypoparathyroidism and persistent hyperparathyroidism. |
| | |
Authors:
|
P E Goretzki; C Dotzenrath; H D Roeher |
Related Documents
:
|
3149814 - Recurrent lead poisoning in a child with immobilization osteoporosis. 19387474 - Vitamin k deficiency in ckd patients: a modifiable risk factor for vascular calcification? 15636434 - Hypoparathyroidism and co-existing celiac disease. 3927224 - Vitamin d deficiency and otosclerosis. 9554194 - Acute cholecystitis in aids patients: correlation of tc-99m hepatobiliary scintigraphy ... 599364 - Epidemiological studies on patients with a persistent vegetative state. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: World journal of surgery Volume: 15 ISSN: 0364-2313 ISO Abbreviation: World J Surg Publication Date: 1991 Nov-Dec |
Date Detail:
|
Created Date: 1992-02-20 Completed Date: 1992-02-20 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7704052 Medline TA: World J Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 693-7 Citation Subset: IM |
Affiliation:
|
Department of Surgery, Heinrich-Heine-Universität, Düsseldorf, Federal Republic of Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Humans Hyperparathyroidism / diagnosis, etiology*, therapy Multiple Endocrine Neoplasia / complications* Parathyroidectomy Recurrence |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Malignant tumor mortality in groups of female medical workers
Next Document: The molecular biology of parathyroid disease.