Document Detail

Management of primary herpes in pregnancy complicated by ruptured membranes and extreme prematurity: case report.
MedLine Citation:
PMID:  3808528     Owner:  NLM     Status:  MEDLINE    
A case of primary herpes simplex vaginitis during pregnancy became complicated by rupture of membranes at 25.5 weeks' gestation. The patient was treated with intravenous acyclovir shortly after rupture, and managed expectantly. Genital lesions rapidly abated, and the infant was delivered by cesarean section at 26.5 weeks' gestation after labor ensued. Transplacental passage of acyclovir was documented. The infant then was treated with a ten-day course of intravenous acyclovir. The infant has remained culture negative for 12 months after delivery.
K Utley; P Bromberger; L Wagner; H Schneider
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  69     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-03-17     Completed Date:  1987-03-17     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  471-3     Citation Subset:  AIM; IM    
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MeSH Terms
Acyclovir / therapeutic use*
Cesarean Section
Fetal Membranes, Premature Rupture / etiology*
Herpes Genitalis / complications,  drug therapy*,  transmission
Infant, Newborn
Infant, Premature*
Pregnancy Complications, Infectious / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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