Document Detail

Management of premature rupture of the membranes.
MedLine Citation:
PMID:  683624     Owner:  NLM     Status:  MEDLINE    
A 14-month prospective study of patients with premature rupture of the membranes was performed. The purpose of the study was to determine the effect of different therapeutic regimens for management of premature rupture of the membranes (PROM) on perinatal morbidity and mortality, as well as on maternal morbidity. Maternal and fetal risk factors and predictive factors in pregnancy outcome were prospectively defined. In patients with PROM whose gestational age was 34 weeks or more, induction within the first 12 hours of membrane rupture resulted in minimal maternal and fetal morbidity and mortality. Patients with gestational age of less than 34 weeks had an improved maternal and fetal outcome if left alone until spontaneous labor or 34 weeks' gestation was reached unless signs of sepsis developed. Respiratory distress syndrome (RDS) was the leading cause of morbidity and mortality in the infants of patients who delivered prematurely due to premature rupture of the membranes. Incidence of fetal infection was significantly less than that of RDS as a cause for fetal morbidity and mortality.
J A Fayez; A A Hasan; H S Jonas; G L Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  52     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-10-18     Completed Date:  1978-10-18     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  17-21     Citation Subset:  AIM; IM    
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MeSH Terms
Bacterial Infections / epidemiology
Fetal Diseases / epidemiology,  mortality,  prevention & control
Fetal Membranes, Premature Rupture / epidemiology,  etiology,  therapy*
Gestational Age
Infant, Newborn
Infant, Newborn, Diseases / epidemiology,  mortality
Labor, Induced
Prospective Studies
Respiratory Distress Syndrome, Newborn / epidemiology,  mortality

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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