Document Detail

Management of postoperative ileus.
MedLine Citation:
PMID:  22385598     Owner:  NLM     Status:  MEDLINE    
Postoperative ileus, a temporary cessation in bowel motility, is a common and significant complication of major surgery. Consequences of postoperative ileus include increased patient discomfort, delayed time to adequate nutrition, prolonged length of stay, and increased cost to the patient and healthcare system. The traditional, multi-modal approach to the resolution of postoperative ileus includes opioid minimization, early ambulation, and early feeding. Newer medications, such as methlynaltrexone and alvimopan (which are peripherally acting mu opioid receptor antagonists), have become available and have proven beneficial for use with postoperative ileus.
Melissa Thompson; Barbara Magnuson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Orthopedics     Volume:  35     ISSN:  1938-2367     ISO Abbreviation:  Orthopedics     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-05     Completed Date:  2012-07-12     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  7806107     Medline TA:  Orthopedics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  IM    
Copyright Information:
Copyright 2012, SLACK Incorporated.
Department of Pharmacy, University of Kentucky Hospital, 800 Rose St, H110, Lexington, KY 40536-2093, USA.
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MeSH Terms
Combined Modality Therapy
Exercise Therapy / methods*
Gastrointestinal Agents
Ileus / therapy*
Naltrexone / analogs & derivatives*,  therapeutic use
Narcotic Antagonists
Piperidines / therapeutic use*
Postoperative Complications / therapy*
Quaternary Ammonium Compounds / therapeutic use
Reg. No./Substance:
0/Gastrointestinal Agents; 0/Narcotic Antagonists; 0/Piperidines; 0/Quaternary Ammonium Compounds; 16590-41-3/Naltrexone; 677C126AET/alvimopan; 83387-25-1/methylnaltrexone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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