Document Detail

Management of periocular basal cell carcinoma by Mohs micrographic surgery.
MedLine Citation:
PMID:  22551161     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: To determine the success of Mohs micrographic surgery (MMS) for periocular basal cell carcinoma (BCC) at a tertiary referral centre in the UK.
DESIGN: A retrospective interventional case series covering 5 years of practice.
METHODS: Review of medical records of 104 consecutive patients who underwent MMS for confirmed periocular BCC. The main outcome measure was biopsy-proven recurrence of BCC at the same anatomical location after MMS. Secondary outcome measures included tumour site, histological subtype and length of follow-up.
RESULTS: 104 patients underwent MMS for periocular BCC from January 2003 to July 2008. 63 (62%) of the surgeries were for primary BCC and 25 procedures (25%) were for recurrent or residual BCC. 64% of tumours were nodular BCC. The mean follow-up was 28 months (range 1-85 months). Six recurrences were identified in total. The recurrence rate following MMS for primary BCC was 1.6% (1 patient) compared to 20% (5 patients) in the patient group treated for residual or recurrent tumours. The mean time to recurrence was 39 months (range 16-71 months).
CONCLUSIONS: MMS for primary BCC has a very high success rate but the recurrence rate increases significantly in cases of recurrent or residual tumours.
Andre S Litwin; Ed Rytina; Thomas Ha; Cornelius René; Simon A Woodruff
Publication Detail:
Type:  Journal Article     Date:  2012-07-10
Journal Detail:
Title:  The Journal of dermatological treatment     Volume:  24     ISSN:  1471-1753     ISO Abbreviation:  J Dermatolog Treat     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-04-29     Completed Date:  2013-06-18     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8918133     Medline TA:  J Dermatolog Treat     Country:  England    
Other Details:
Languages:  eng     Pagination:  232-4     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Carcinoma, Basal Cell / pathology,  surgery*
Eyelid Neoplasms / pathology,  surgery*
Follow-Up Studies
Middle Aged
Mohs Surgery*
Neoplasm Recurrence, Local* / pathology,  surgery
Prospective Studies
Retrospective Studies
Skin Neoplasms / pathology,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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