Document Detail


Management of patients with nephrotic syndrome.
MedLine Citation:
PMID:  19680831     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrotic syndrome is characterised by proteinuria >3.5 g/24h, oedema, hypoalbuminaemia and hyperlipidaemia. Several glomerular diseases, either primary or secondary, may lead to nephrotic syndrome. Investigations for nephrotic syndrome include immunological and infectious evaluations. Renal biopsy is often mandatory, except in diabetes. Depending on aetiology specific treatment, often with immunosuppressive agents, may be implemented. In any cases nonspecific treatment should be started with ACE inhibitors or ARBs. Urinary protein loss leads to several complications: water and sodium retention, hyperlipidaemia, increased risk of thromboembolism and infection, anaemia and alteration of mineral metabolism. Each of these complications must be identified.
Authors:
S de Seigneux; P Y Martin
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Swiss medical weekly     Volume:  139     ISSN:  1424-7860     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-08-14     Completed Date:  2009-10-08     Revised Date:  2011-02-15    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  416-22     Citation Subset:  IM    
Affiliation:
Service de Néphrologie, Département de médecine interne, HUG, Geneva, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Anemia / etiology
Angiotensin II Type 1 Receptor Blockers / therapeutic use*
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Dyslipidemias / etiology
Edema / etiology
Humans
Hypertension / drug therapy,  etiology
Nephrotic Syndrome / complications,  diagnosis,  drug therapy*
Thromboembolism / etiology
Chemical
Reg. No./Substance:
0/Angiotensin II Type 1 Receptor Blockers; 0/Angiotensin-Converting Enzyme Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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