Document Detail

Management for neonatal aspiration syndrome caused by vernix caseosa.
MedLine Citation:
PMID:  15824497     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To clarify resuscitation methods against the lethal vernix caseosa aspiration syndrome. METHOD: A single case report with a literature review. RESULTS: Our case report was associated with aspiration syndrome caused by an airway obstruction of vernix caseosa: a proteolipid biofilm synthesized by the fetus. A 23-year-old woman normally delivered a mature infant at term. The infantile oral cavity was filled with numerous aggregates of vernix caseosa. Two hours after his birth, the infant died from respiratory insufficiency. We discuss the difference between management of our case and the previously reported case. CONCLUSION: Pregnant women with a diffuse pattern of high-level echoes in prenatal ultrasonography, suggesting the presence of massive vernix caseosa, should be transferred to a well-equipped institution that can administer inhaled nitric oxide and extracorporeal membrane oxygenation.
Koji Nishijima; Ken-ichi Shukunami; Shuji Inoue; Fumikazu Kotsuji
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  20     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-04-12     Completed Date:  2005-07-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  194-6     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 S. Karger AG, Basel.
Department of Obstetrics and Gynecology, University of Fukui, Matsuoka-Cho, Yoshida-Gun, Fukui, Japan.
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MeSH Terms
Airway Obstruction / complications,  etiology*,  pathology,  therapy
Fatal Outcome
Infant, Newborn
Intubation, Intratracheal
Lung / pathology
Respiratory Insufficiency / etiology
Vernix Caseosa*

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