Document Detail

Management of a massive pulmonary embolism in a pregnant patient with mechanical fragmentation followed by delayed catheter-directed thrombolysis in the early postpartum period.
MedLine Citation:
PMID:  18609358     Owner:  NLM     Status:  MEDLINE    
There are limited data available on the management of massive pulmonary embolism in pregnancy. The use of systemic thrombolysis has been reported, but there are few documented cases on the use of mechanical fragmentation or catheter-directed thrombolysis. Systemic thrombolysis in pregnancy increases the risk of major hemorrhage and there are reports of massive subchorionic hematomas following its use. We describe the use of mechanical fragmentation and optional retrievable inferior vena cava (IVC) filter insertion in a 38-week pregnant woman followed by delayed pharmacological catheter-directed thrombolysis during the early postpartum period to successfully treat a massive pulmonary embolism.
S A O'Keeffe; A McGrath; J M Ryan; B Byrne
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  21     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-19     Completed Date:  2008-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  591-4     Citation Subset:  IM    
Department of Radiology, St James's Hospital, Dublin, Ireland.
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MeSH Terms
Catheterization* / methods
Fibrinolytic Agents / therapeutic use
Postpartum Period* / drug effects
Pregnancy Complications, Cardiovascular / drug therapy*,  radiography
Pulmonary Artery / radiography
Pulmonary Embolism / drug therapy*,  radiography
Thrombolytic Therapy / methods*
Reg. No./Substance:
0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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