Document Detail

Management of low-output pancreatic fistulas with fibrin glue.
MedLine Citation:
PMID:  15219492     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Despite advances in surgical, endoscopic, and percutaneous therapeutic techniques, pancreatic fistulas remain a source of significant morbidity and long-term patient discomfort. The intraoperative use of fibrin sealant has been used prophylactically to prevent formation of fistula. We recognized the potential use of fibrin glue as a therapeutic modality for successful resolution of low-output pancreatic fistulas. METHODS: Three patients with low (<20 ml per day) output pancreatic fistulas underwent fluoroscopically directed injection of fibrin glue along their fistula tract. RESULTS: All 3 patients underwent successful fibrin glue injection without procedural complication. All fistula output stopped, and the 3 patients remained asymptomatic at 1 year. CONCLUSIONS: Fibrin glue inserted with image-guided catheter delivery systems may be a useful option in selected patients with low-output pancreatic fistulas.
C Clay Cothren; Robert C McIntyre; Stephen Johnson; Gregory V Stiegmann
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  188     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-06-28     Completed Date:  2004-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-91     Citation Subset:  AIM; IM    
Department of Surgery, Denver Health Medical Center, 777 Bannock St., MC 0206, Denver, CO 80204, USA.
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MeSH Terms
Fibrin Tissue Adhesive / therapeutic use*
Middle Aged
Pancreatic Fistula / radiography,  therapy*
Postoperative Complications / therapy
Radiography, Interventional / methods*
Tissue Adhesives / therapeutic use*
Reg. No./Substance:
0/Fibrin Tissue Adhesive; 0/Tissue Adhesives

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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