| Management of local recurrence of colorectal cancer: the role of PET/CT. | |
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MedLine Citation:
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PMID: 20661560 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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AIM: The aim was to examine the clinical applicability of positron-emission tomography/computed tomography (PET/CT) for diagnosing local recurrence of colorectal cancer. METHODS: From August 2003 to August 2008, 256 patients with colorectal cancer underwent PET/CT scanning for staging or restaging. Local recurrence was detected in 22 patients (18 men, 4 women) postsurgically. RESULTS: Of the 22 patients, 21 (95.5%) underwent positive 2-[fluorine-18]-fluoro-2-deoxy-D: -glucose uptake and were diagnosed with local recurrence by PET/CT; the results were negative in one case (4.5%). The sensitivity, specificity, positive predictive value, and negative predictive value for local recurrence were 95.5%, 100%, 100%, and 99.6%, respectively. CT/MRI scans yielded the following results: positive, 10 cases (45.5%); suspected positive, 11 cases (50.0%); negative, 1 case (4.5%). In the suspected positive cases, not only imaging but also colonoscopy and tumor markers among other techniques were used for definitive diagnosis. CONCLUSION: PET/CT has high sensitivity and specificity for diagnosing local recurrence of colorectal cancer and would be useful especially in the case of locally recurrent colorectal cancer suspected to be positive by CT/MRI. |
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Authors:
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Yoshiko Bamba; Michio Itabashi; Shingo Kameoka |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Abdominal imaging Volume: 36 ISSN: 1432-0509 ISO Abbreviation: Abdom Imaging Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 322-6 Citation Subset: IM |
Affiliation:
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Department of Surgery II, Tokyo Women's Medical University, 8-1, Kawadacho Shinjuku-ku, Tokyo, 162-8666, Japan, tkichi@live.jp. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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