Document Detail


Management of learned food aversions in cancer patients receiving chemotherapy.
MedLine Citation:
PMID:  3677112     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aversions that form towards foods after their ingestion has been associated with illness are termed learned food aversions (LFA). This adverse treatment side effect has been implicated in the anorexia of cancer and can compromise the quality of patients' lives. In an attempt to block the formation or ameliorate the manifestations of this treatment sequela, a nutritionally inconsequential "scapegoat" food was presented to patients just prior to their first course of therapy. The hypothesis was that treatment-related aversions would be targeted towards the scapegoat, thereby sparing acceptable and nutrient-dense items in the patient's typical diet. LFA were observed in 55.3% of 76 patients receiving chemotherapy for different cancers. Following formation of a scapegoat aversion, the incidence of LFA was only 11.1% (two of 18) during the 6-month follow-up period. In contrast, 48.4% (15 of 31) of the patients not exposed to the scapegoat formed LFA. More than twice as many patients with treatment-related LFA had a pretreatment histology of the problem, suggesting the presence of a subgroup of high-risk patients. Strategies for improving upon the present results are discussed.
Authors:
R D Mattes; C Arnold; M Boraas
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cancer treatment reports     Volume:  71     ISSN:  0361-5960     ISO Abbreviation:  Cancer Treat Rep     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-12-31     Completed Date:  1987-12-31     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7607107     Medline TA:  Cancer Treat Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1071-8     Citation Subset:  IM    
Affiliation:
Monell Chemical Senses Center, Philadelphia, PA 19104.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Antineoplastic Agents / adverse effects*
Avoidance Learning*
Cachexia / prevention & control
Female
Food Habits*
Humans
Male
Middle Aged
Nausea / chemically induced
Neoplasms / drug therapy,  psychology*
Questionnaires
Vomiting / chemically induced
Grant Support
ID/Acronym/Agency:
CA-37298/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

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