Document Detail


Management of late recurrence of a low-grade endometrial stromal sarcoma (LGESS): treatment with letrozole.
MedLine Citation:
PMID:  17972504     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Low grade endometrial stromal sarcoma (LGESS) is a rare disease. LGESS usually expresses steroidal receptors and is regarded to be hormone-sensitive. Due to the rarity of the tumor, only few case series have been published so far. Here, we report the case of a 36-year-old woman who underwent an abdominal hysterectomy with bilateral salpingo-oophorectomy and adjuvant radiotherapy for a G1 LGESS in 1991. Twelve years later she presented to us with pelvic and peritoneal masses. The patient was treated with letrozole achieving a partial response which is lasting 39 months. Treatment is ongoing. Aromatase inhibitors represent an interesting treatment option for LGESS.
Authors:
K Krauss; C Bachmann; J T Hartmann; K Siegmann; K Sotlar; D Wallwiener; J Huober
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  27     ISSN:  0250-7005     ISO Abbreviation:  Anticancer Res.     Publication Date:    2007 Sep-Oct
Date Detail:
Created Date:  2007-11-01     Completed Date:  2007-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  3477-80     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Eberhard-Karls-University Tuebingen, Calwestr. 7, D-72076 Tuebingen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antineoplastic Agents / therapeutic use*
Endometrial Stromal Tumors / drug therapy*,  pathology,  prevention & control*
Female
Humans
Muscle Neoplasms / secondary
Nitriles / therapeutic use*
Psoas Muscles / pathology
Radiography, Abdominal
Recurrence
Tomography, X-Ray Computed
Triazoles / therapeutic use*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Nitriles; 0/Triazoles; 112809-51-5/letrozole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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