| Management of hyponatremia: providing treatment and avoiding harm. | |
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MedLine Citation:
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PMID: 20889809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hyponatremia, in its most severe form, requires urgent infusion of hypertonic saline to correct cerebral edema. However, overly rapid correction of chronic hyponatremia can cause osmotic demyelination syndrome. The authors review the treatment of hyponatremia in order to provide clinicians with a sound approach in a variety of settings in which severity, symptoms, and underlying disease states influence therapy. Also discussed is the current role of vasopressin antagonists in treatment. |
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Authors:
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Chirag Vaidya; Warren Ho; Benjamin J Freda |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cleveland Clinic journal of medicine Volume: 77 ISSN: 1939-2869 ISO Abbreviation: Cleve Clin J Med Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2010-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703441 Medline TA: Cleve Clin J Med Country: United States |
Other Details:
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Languages: eng Pagination: 715-26 Citation Subset: IM |
Affiliation:
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Tufts University School of Medicine, Renal Division, Baystate Medical Center, MA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain Edema
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etiology Demyelinating Diseases / etiology Diuretics / adverse effects, therapeutic use Extracellular Fluid Fibrosis Fluid Therapy Humans Hyponatremia / complications, diagnosis*, drug therapy* Inappropriate ADH Syndrome / etiology Osmolar Concentration Practice Guidelines as Topic Receptors, Vasopressin / antagonists & inhibitors Saline Solution, Hypertonic / administration & dosage, adverse effects, therapeutic use* Sodium / adverse effects, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Diuretics; 0/Receptors, Vasopressin; 0/Saline Solution, Hypertonic; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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