Document Detail

Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.
MedLine Citation:
PMID:  15231951     Owner:  NLM     Status:  MEDLINE    
Jaundice occurs in most newborn infants. Most jaundice is benign, but because of the potential toxicity of bilirubin, newborn infants must be monitored to identify those who might develop severe hyperbilirubinemia and, in rare cases, acute bilirubin encephalopathy or kernicterus. The focus of this guideline is to reduce the incidence of severe hyperbilirubinemia and bilirubin encephalopathy while minimizing the risks of unintended harm such as maternal anxiety, decreased breastfeeding, and unnecessary costs or treatment. Although kernicterus should almost always be preventable, cases continue to occur. These guidelines provide a framework for the prevention and management of hyperbilirubinemia in newborn infants of 35 or more weeks of gestation. In every infant, we recommend that clinicians 1) promote and support successful breastfeeding; 2) perform a systematic assessment before discharge for the risk of severe hyperbilirubinemia; 3) provide early and focused follow-up based on the risk assessment; and 4) when indicated, treat newborns with phototherapy or exchange transfusion to prevent the development of severe hyperbilirubinemia and, possibly, bilirubin encephalopathy (kernicterus).
Publication Detail:
Type:  Guideline; Journal Article; Practice Guideline    
Journal Detail:
Title:  Pediatrics     Volume:  114     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-02     Completed Date:  2004-09-30     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  297-316     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bilirubin / blood
Breast Feeding
Exchange Transfusion, Whole Blood
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / therapy
Jaundice, Neonatal / etiology,  prevention & control,  therapy*
Kernicterus / prevention & control*
Risk Assessment
Terminology as Topic
Reg. No./Substance:
Comment In:
Pediatrics. 2004 Oct;114(4):1086-8   [PMID:  15466110 ]
Pediatrics. 2004 Oct;114(4):1134-5; author reply 1135-7   [PMID:  15466132 ]
Pediatrics. 2004 Aug;114(2):494-6   [PMID:  15286239 ]
Pediatrics. 2009 Oct;124(4):1193-8   [PMID:  19786452 ]
Pediatrics. 2005 Mar;115(3):824-5   [PMID:  15741399 ]
Pediatrics. 2006 Jan;117(1):262-3   [PMID:  16396898 ]
Erratum In:
Pediatrics. 2004 Oct;114(4):1138

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cerebral metabolism in severe neonatal hyperbilirubinemia.
Next Document:  E-mail communication between pediatricians and their patients.