| Management of granulomatous common variable immunodeficiency diagnosed in pregnancy: a case report. | |
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MedLine Citation:
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PMID: 22538377 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Common variable immunodeficiency (CVID) is a rare condition that affects women of childbearing age with important implications in pregnancy. It is characterised by low immunoglobulins (Igs), poor antibody response and a susceptibility to recurrent infections. The cornerstone of management of CVID is Ig replacement. As the transfer of IgG across the placenta in the third trimester of pregnancy is necessary for protection of the infant in the first months of life, failure to recognise this condition and treat it appropriately can have adverse consequences for the neonate, as well as the mother. Here we describe the complex perinatal medical management of a 34-year-old woman who was diagnosed with CVID in the 26th week of pregnancy. |
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Authors:
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A L Manson; S Zaheri; P Kelleher; S Wakelin; C Nelson-Piercy; S L Seneviratne; N Cooper |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 32 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 387-9 Citation Subset: IM |
Affiliation:
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Department of Clinical Immunology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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