Document Detail

Management of gout.
MedLine Citation:
PMID:  760433     Owner:  NLM     Status:  MEDLINE    
Although the traditional oral colchicine regimen is often used for the acute attack, the intravenous route has advantages. Indomethacin, phenylbutazone, oxyphenbutazone and the newer nonsteroidal anti-inflammatory agents, such as ibuprofen, naproxen and fenoprofen, are quite successful. For chronic management of hyperuricemia, it is helpful to distinguish between overproducers of uric acid, for whom allopurinol is the rational therapy, and underexcreters of uric acid, for whom probenecid or sulfinpyrazone is indicated.
G V Gordon; H R Schumacher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American family physician     Volume:  19     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1979-03-13     Completed Date:  1979-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  91-7     Citation Subset:  AIM; IM    
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MeSH Terms
Allopurinol / administration & dosage,  therapeutic use
Colchicine / administration & dosage,  therapeutic use
Gout / diagnosis,  drug therapy*,  metabolism
Phenylbutazone / therapeutic use
Probenecid / therapeutic use
Sulfinpyrazone / therapeutic use
Reg. No./Substance:
315-30-0/Allopurinol; 50-33-9/Phenylbutazone; 57-66-9/Probenecid; 57-96-5/Sulfinpyrazone; 64-86-8/Colchicine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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